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Assessment of glomerular filtration rate and serum creatinine levels in the diagnosis of chronic kidney disease in adults - Brief INAHTA

Health technology assessment - Posted on Dec 28 2011

- To assess the performance of three equations for estimation of GFR: CG, MDRD, CKD-EPI. The equation showing the least bias, best precision and best accuracy compared to the GFR measured by exogenous marker was considered the most useful

- To assess the analytical performance of methods for measurement of serum creatinine concentrations, compared with a reference method: isotopic dilution mass spectrometry. The analysis was not performed in analyser / reagent pairs but by Jaffé or enzymatic assay methods

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