BOTOX
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                        Opinions on drugs - 
	
		Posted on 
	
		
			Jul 18 2012
		
		
	
	
						
							
							 - Updated on 
							
								
									Aug 01 2012
								
								
							
							
						
                    
                Reason for request
										Inclusion on the list of medicines approved for hospital use in the extension of the indication: “the management of urinary incontinence with neurogenic detrusor overactivity due to spinal cord injury or multiple sclerosis, who are not adequately managed with anticholinergics and who are catheterising”.
									
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Clinical Benefit
| Substantial | The actual benefit of BOTOX is substantial. | 
Clinical Added Value
| moderate | BOTOX provides a moderate improvement in actual benefit (IAB III) in the treatment of urinary incontinence with neurogenic detrusor overactivity in spinal cord injury patients and patients with multiple sclerosis who are not adequately managed with anticholinergics and who are catheterising as a method of passing urine. | 
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