ZYKADIA (ceritinib), tyrosine kinase inhibitor

ONCOLOGY - new medicinal product
Opinions on drugs - Posted on Jan 29 2016

Reason for request

Inclusion

Minor improvement in the treatment of adults with ALK+ advanced non-small cell lung cancer previously treated with crizotinib

 

  • ZYKADIA has conditional Marketing Authorisation as monotherapy for the treatment of adult patients with anaplastic lymphoma kinase (ALK+) advanced non-small cell lung cancer previously treated with crizotinib.
  • Its efficacy in the third-line treatment of ALK+ lung cancer has been demonstrated in a non-comparative study primarily in terms of overall response rate.
  • We still await comparative data versus chemotherapy.

Clinical Benefit

Substantial

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Clinical Added Value

minor

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Therapeutic use

-

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