Reason for request

Re-assessment of the actual benefit (AB) as a curative influenza treatment during periods of virus circulation and during an influenza pandemic in accordance with article R 163 12 of the Social Security Code. Extension of indication to children less than 1 year of age during an influenza pandemic outbreak as curative and prophylactic treatment of influenza.

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Clinical Benefit

Low

The actual benefit of TAMIFLU as a curative influenza treatment, when initiated within 48 hours of the onset of symptoms, during a period of ordinary influenza epidemic or a pandemic period is low in :
- subjects with clinical presentation of influenza judged severe by the physicians or complicated from outset,
- subjects with particular risk factors 16, including pregnant women.

The actual benefit as a curative treatment in pandemic periods is low in children less than 12 months of age.

 

Insufficient

The actual benefit in influenza treatment is insufficient in other situations.

The actual clinical benefit as a prophylactic treat ment in pandemic periods is insufficient in children less than 12 months of age.


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Évaluation des médicaments

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