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Reason for request
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Clinical Benefit
| Low |
The actual benefit of GENOTONORM in children born small for gestational age with a birth weight and/or length of < -2 SD who failed to show catch-up growth (growth rate < 0 SD during the last year) by 4 years of age or later and with growth failure (current height less than or equal to -3 SD and parental adjusted height < -1 DS) is low. |
| Substantial |
The actual benefit of GENOTONORM in Turner syndrome is substantial. |
Clinical Added Value
| minor |
GENOTONORM provides about a minor improvement in actual benefit (IAB IV) in the treatment of Turner syndrome and chronic renal disease. |
| no clinical added value |
GENOTONORM does not provide about an improvement in actual benefit (IAB V) in the therapeutic strategy in children born small for gestational age. |
Documents
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GENOTONORM 07122011 AVIS CT5437
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Document court "L’hormone de croissance chez l’enfant non déficitaire, évaluation du service rendu à la collectivité"
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Document long "L’hormone de croissance chez l’enfant non déficitaire, évaluation du Service Rendu à la Collectivité"
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Synthèse d'avis HORMONES DE CROISSANCE
