Reason for request
Inclusion
Clinical Benefit
| Substantial |
The actual benefit of PLENADREN is substantial. |
Clinical Added Value
| minor |
The PLENADREN modified-release dosage form of hydrocortisone is closer to the pharmacokinetic profile of the physiological rhythm of cortisol, without any clinical consequence having been demonstrated. Consequently, PLENADREN provides a minor improvement in actual benefit (IAB IV) in the care of patients with adrenal insufficiency. |
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