Reason for request

Modification of the listing conditions

Key points

Favourable opinion for maintenance of reimbursement in the MA indication: “COSENTYX, alone or in combination with methotrexate (MTX), is indicated for the treatment of active psoriatic arthritis in adult patients when the response to previous disease-modifying anti-rheumatic drug (DMARD) therapy has been inadequate.”


Clinical Benefit

Moderate

The Committee deems that the clinical benefit of COSENTYX 150 mg and 300 mg (secukinumab) solution for injection in pre-filled syringe and pen remains moderate in this MA indication.


Clinical Added Value

no clinical added value

In the absence of:

  • robust comparative data versus the other biological medicinal products available,
  • and specific data in patients intolerant or responding inadequately to at least one TNF inhibitor,

the Committee deems that COSENTYX 150 mg and 300 mg (secukinumab) solution for injection in pre-filled syringe and pen provide no clinical added value (CAV V) in the current care pathway, which includes the relevant comparators.


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